Inducing different severities of traumatic brain injury inDrosophilausing a piezoelectric actuator

Janani Saikumar, Joshua Kim, China N. Byrns, Matthew Hemphill, David F. Meaney, Nancy M. Bonini

Published: 2020-12-03 DOI: 10.1038/s41596-020-00415-y

Drosophila

Traumatic Brain Injury

Piezoelectric Actuator

Neurodegeneration Model

Genetic Screens

AI 解读

Genetic manipulation and immortalized culture of ex vivo primary human germinal center B cells

The cell-line-derived subcutaneous tumor model in preclinical cancer research

Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses

NovoSpaRc: flexible spatial reconstruction of single-cell gene expression with optimal transport

Genome-wide pooled CRISPR screening in neurospheres

High-throughput cultivation and identification of bacteria from the plant root microbiota

Viral crosslinking and solid-phase purification enables discovery of ribonucleoprotein complexes on incoming RNA virus genomes

Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility

Addendum: Micro-CT acquisition and image processing to track and characterize pulmonary nodules in mice

Multiplexed single-cell proteomics using SCoPE2

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Drosophila models have been instrumental in providing insights into molecular mechanisms of neurodegeneration, with wide application to human disease. The brain degeneration associated with traumatic brain injury (TBI) has been modeled in Drosophila using
Introduction
Materials
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Troubleshooting
Timing
Anticipated results
References
ACKNOWLEDGMENTS

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Inducing different severities of traumatic brain injury inDrosophilausing a piezoelectric actuator

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