Hyperspectral confocal imaging for high-throughput readout and analysis of bio-integrated microlasers

Vera M. Titze, Soraya Caixeiro, Vinh San Dinh, Matthias König, Matthias Rübsam, Nachiket Pathak, Anna-Lena Schumacher, Maximilian Germer, Christian Kukat, Carien M. Niessen, Marcel Schubert, Malte C. Gather

Published: 2024-01-18 DOI: 10.1038/s41596-023-00924-6

bio-integrated microlasers

hyperspectral confocal imaging

high-throughput readout

intracellular biosensing

multiplexed cell tracking

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Supplementary information

Supplementary Information

Supplementary Notes 1–3, Figs. 1–15 and Tables 1–3

Reporting Summary

Supplementary Video

Dynamic refractive index sensing of glucose diffusion. x-y maximum intensity projection (MIP) (left) and x-z MIP (center) of the hyperspectral confocal z-stack, color-coded by fitted refractive index, with exemplary raw lasing spectra and calculated external refractive index changes (right). All panels are synchronized.

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References

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Hyperspectral confocal imaging for high-throughput readout and analysis of bio-integrated microlasers

Supplementary information

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