Genome-wide and sister chromatid-resolved profiling of protein occupancy in replicated chromatin with ChOR-seq and SCAR-seq

Nataliya Petryk, Nazaret Reverón-Gómez, Cristina González-Aguilera, Maria Dalby, Robin Andersson, Anja Groth

Published: 2021-08-05 DOI: 10.1038/s41596-021-00585-3

ChOR-seq

SCAR-seq

chromatin occupancy

histone modifications

cell cycle dynamics

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Elucidating the mechanisms underlying chromatin maintenance upon genome replication is critical for the understanding of how gene expression programs and cell identity are preserved across cell divisions. Here, we describe two recently developed technique
Introduction
Materials
Procedure 1: ChOR-seq
Procedure 2: SCAR-seq
Troubleshooting
Timing
- Procedure 1: ChOR-seq
- Procedure 2: SCAR-seq
Anticipated results
References
ACKNOWLEDGMENTS

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Genome-wide and sister chromatid-resolved profiling of protein occupancy in replicated chromatin with ChOR-seq and SCAR-seq

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