Fabrication, characterization and applications of graphene electronic tattoos

Dmitry Kireev, Shideh Kabiri Ameri, Alena Nederveld, Jameson Kampfe, Hongwoo Jang, Nanshu Lu, Deji Akinwande

Published: 2021-04-11 DOI: 10.1038/s41596-020-00489-8

Graphene Electronic Tattoos

Wearable Technology

Biopotential Monitoring

Low-Cost Fabrication

Skin-Integrated Devices

AI 解读

Author Correction: Full-length sequencing of circular DNA viruses and extrachromosomal circular DNA using CIDER-Seq

Generation of heart-forming organoids from human pluripotent stem cells

Design and fabrication of wearable electronic textiles using twisted fiber-based threads

Activation of mechanoluminescent nanotransducers by focused ultrasound enables light delivery to deep-seated tissue in vivo

Chromatin accessibility profiling by ATAC-seq

Deoxyfluorination of phenols for chemoselective18F-labeling of peptides

Author Correction: cfSNV: a software tool for the sensitive detection of somatic mutations from cell-free DNA

Human primordial germ cell-like cells specified from resetting precursors develop in human hindgut organoids

An inexpensive semi-automated sample processing pipeline for cell-free RNA extraction

Application of CHyMErA Cas9-Cas12a combinatorial genome-editing platform for genetic interaction mapping and gene fragment deletion screening

查看全部

Sections

Figures

References

Numerous fields of science and technology, including healthcare, robotics and bioelectronics, have begun to switch their research direction from developing ‘high-end, high-cost’ tools towards ‘high-end, low-cost’ solutions
Introduction
Materials
Procedure
Troubleshooting
Timing
Anticipated results
- Reporting Summary
- References
References
ACKNOWLEDGMENTS

Kim, D.-H. et al. Epidermal electronics. Science 333, 838–843 (2011).
Flores, M., Glusman, G., Brogaard, K., Price, N. D. & Hood, L. P4 medicine: how systems medicine will transform the healthcare sector and society. Per. Med. 10, 565–576 (2013).
Becker, S. et al. mHealth 2.0: experiences, possibilities, and perspectives. JMIR mHealth uHealth 2, e24 (2014).
Chow, C. K., Ariyarathna, N., Islam, S. M. S., Thiagalingam, A. & Redfern, J. mHealth in cardiovascular health care. Heart Lung Circ. 25, 802–807 (2016).
Price, M. et al. mHealth: A mechanism to deliver more accessible, more effective mental health care. Clin. Psychol. Psychother. 21, 427–436 (2014).
Ray, T. R. et al. Bio-integrated wearable systems: a comprehensive review. Chem. Rev. 119, 5461–5533 (2019).
Mukhopadhyay, S. C. Wearable sensors for human activity monitoring: a review. IEEE Sens. J. 15, 1321–1330 (2015).
Heikenfeld, J. et al. Wearable sensors: modalities, challenges, and prospects. Lab Chip 18, (2017).
Neethirajan, S. Recent advances in wearable sensors for animal health management. Sens. Bio-Sensing Res 12, 15–29 (2017).
Guk, K. et al. Evolution of wearable devices with real-time disease monitoring for personalized healthcare. Nanomaterials 9, 1–23 (2019).
Wearable Technology Market—Growth, Trends, and Forecasts (2020–2025). https://www.researchandmarkets.com/reports/4591296/wearable-technology-market-growth-trends-and
Wang, C. et al. Monitoring of the central blood pressure waveform via a conformal ultrasonic device. Nat. Biomed. Eng. 2, 687–695 (2018).
Gutruf, P. et al. Fully implantable optoelectronic systems for battery-free, multimodal operation in neuroscience research. Nat. Electron. 1, 652–660 (2018).
Miro, P. et al. An atlas of two-dimensional materials. Chem. Soc. Rev. 43, 6537–6554 (2014).
Ferrari, A. C. et al. Science and technology roadmap for graphene, related two-dimensional crystals, and hybrid systems. Nanoscale 7, 4598–4810 (2015).
Chhowalla, M., Jena, D. & Zhang, H. Two-dimensional semiconductors for transistors. Nat. Rev. Mater 1, 16052 (2016).
Bhimanapati, G. R. et al. Recent advances in two-dimensional materials beyond graphene. ACS Nano 9, 11509–11539 (2015).
Kireev, D., Offenhaeusser, A. & Offenhäusser, A. Graphene & two-dimensional devices for bioelectronics and neuroprosthetics. 2D Mater 5, 042004 (2018).
Hess, L. H., Seifert, M. & Garrido, J. A. Graphene transistors for bioelectronics. Proc. IEEE 101, 1780–1792 (2013).
Kireev, D. et al. Graphene transistors for interfacing with cells: towards a deeper understanding of liquid gating and sensitivity. Sci. Rep. 7, 6658 (2017).
Kireev, D. et al. Graphene multielectrode arrays as a versatile tool for extracellular measurements. Adv. Healthc. Mater. 6, 1601433 (2017).
Kabiri Ameri, S. et al. Graphene electronic tattoo sensors. ACS Nano 11, 7634–7641 (2017).
Ameri, S. K. et al. Imperceptible electrooculography graphene sensor system for human–robot interface. npj 2D Mater. Appl. 2, 19 (2018).
Sel, K. et al. Electrical characterization of graphene-based e-tattoos for bio-impedance-based physiological sensing. BioCAS 2019 - Biomed. Circuits Syst. Conf. Proc. 1–4 (2019). https://doi.org/10.1109/BIOCAS.2019.8919003
Zhang, X. et al. Ultrasensitive field‐effect biosensors enabled by the unique electronic properties of graphene. Small 16, 1902820 (2020).
Huang, H. et al. Graphene-based sensors for human health monitoring. Front. Chem. 7, 1–26 (2019).
Wassei, J. K. & Kaner, R. B. Graphene, a promising transparent conductor. Mater. Today 13, 52–59 (2010).
Das, T., Sharma, B. K., Katiyar, A. K. & Ahn, J.-H. H. Graphene-based flexible and wearable electronics. J. Semicond. 39, 011007 (2018).
Park, D. et al. Fabrication and utility of a transparent graphene neural electrode array for electrophysiology, in vivo imaging, and optogenetics. Nat. Protoc. 11, 2201–2222 (2016).
Song, J.-K. et al. Wearable force touch sensor array using a flexible and transparent electrode. Adv. Funct. Mater. 27, 1605286 (2017).
Yang, S. et al. “Cut-and-paste” manufacture of multiparametric epidermal sensor systems. Adv. Mater. 27, 6423–6430 (2015).
Wang, Y. et al. Low-cost, μm-thick, tape-free electronic tattoo sensors with minimized motion and sweat artifacts. npj Flex. Electron. 2, 6 (2018).
Stier, A. et al. Stretchable tattoo-like heater with on-site temperature feedback control. Micromachines 9, 170 (2018).
Bae, S. et al. Roll-to-roll production of 30-inch graphene films for transparent electrodes. Nat. Nanotechnol. 5, 574–578 (2010).
DiMarco, J. P. & Philbrick, J. T. Use of ambulatory electrocardiographic (Holter) monitoring. Ann. Intern. Med. 113, 53–68 (1990).
Montain, S. J. & Ely, M. Water Requirements and Soldier Hydration (Borden Institute). https://ke.army.mil/bordeninstitute/other_pub/hydrationpdf.pdf
Sawka, M. N., Cheuvront, S. N. & Kenefick, R. W. High skin temperature and hypohydration impair aerobic performance. Exp. Physiol. 97, 327–332 (2012).
Kumari, P., Mathew, L. & Syal, P. Increasing trend of wearables and multimodal interface for human activity monitoring: a review. Biosens. Bioelectron. 90, 298–307 (2017).
Barea Navarro, R., Boquete Vázquez, L. & López Guillén, E. EOG-based wheelchair control. in Smart Wheelchairs and Brain-Computer Interfaces 381–403 (Elsevier, 2018). https://doi.org/10.1016/B978-0-12-812892-3.00016-9
Sel, K., Ibrahim, B. & Jafari, R. ImpediBands: body coupled bio-impedance patches for physiological sensing proof of concept. IEEE Trans. Biomed. Circuits Syst. 14, 757–774 (2020).
Ibrahim, B. & Jafari, R. A novel method for continuous blood pressure monitoring using wrist-worn bio-impedance sensors. 2018 IEEE Biomed. Circuits Syst. Conf. BioCAS 2018 - Proc. 3–6 (2018). https://doi.org/10.1109/BIOCAS.2018.8584783
Masvidal-Codina, E. et al. High-resolution mapping of infraslow cortical brain activity enabled by graphene microtransistors. Nat. Mater. 18, 280–288 (2019).
Polat, E. O. et al. Flexible graphene photodetectors for wearable fitness monitoring. Sci. Adv. 5, eaaw7846 (2019).
Miao, P. et al. Graphene nanostructure-based tactile sensors for electronic skin applications. Nano-Micro Lett 11, 71 (2019).
Saccomandi, P. et al. Microfabricated tactile sensors for biomedical applications: a review. Biosensors 4, 422–448 (2014).
Chortos, A., Liu, J. & Bao, Z. Pursuing prosthetic electronic skin. Nat. Mater. 15, 937–950 (2016).
Chang, T. H., Li, K., Yang, H. & Chen, P. Y. Multifunctionality and mechanical actuation of 2D materials for skin-mimicking capabilities. Adv. Mater. 30, 1–13 (2018).
Akinwande, D., Petrone, N. & Hone, J. Two-dimensional flexible nanoelectronics. Nat. Commun. 5, 5678 (2014).
Qiao, Y. et al. Graphene-based wearable sensors. Nanoscale 11, 18923–18945 (2019).
Amjadi, M., Kyung, K.-U., Park, I. & Sitti, M. Stretchable, skin-mountable, and wearable strain sensors and their potential applications: a review. Adv. Funct. Mater. 26, 1678–1698 (2016).
Jang, H., Dai, Z., Ha, K.-H., Ameri, S. K. & Lu, N. Stretchability of PMMA-supported CVD graphene and of its electrical contacts. 2D Mater 7, 014003 (2019).
Yetisen, A. K., Martinez-Hurtado, J. L., Ünal, B., Khademhosseini, A. & Butt, H. Wearables in medicine. Adv. Mater. 30, e1706910 (2018).
Tricoli, A., Nasiri, N. & De, S. Wearable and miniaturized sensor technologies for personalized and preventive medicine. Adv. Funct. Mater. 27, 1–19 (2017).
Griss, P., Tolvanen-Laakso, H. K., Meriläinen, P. & Stemme, G. Characterization of micromachined spiked biopotential electrodes. IEEE Trans. Biomed. Eng. 49, 597–604 (2002).
Kirkup, L. & Searle, A. A direct comparison of wet, dry and insulating bioelectric recording electrodes. Physiol. Meas. 21, 271 (2000).
Giffney, T., Bejanin, E., Kurian, A. S., Travas-Sejdic, J. & Aw, K. Highly stretchable printed strain sensors using multi-walled carbon nanotube/silicone rubber composites. Sensors Actuators A Phys 259, 44–49 (2017).
Cheng, Y., Wang, R., Zhai, H. & Sun, J. Stretchable electronic skin based on silver nanowire composite fiber electrodes for sensing pressure, proximity, and multidirectional strain. Nanoscale 9, 3834–3842 (2017).
Herbert, R., Kim, J. H., Kim, Y. S., Lee, H. M. & Yeo, W. H. Soft material-enabled, flexible hybrid electronics for medicine, healthcare, and human-machine interfaces. Materials (Basel) 11, 187 (2018).
Kang, J., Tok, J. B. H. & Bao, Z. Self-healing soft electronics. Nat. Electron. 2, 144–150 (2019).
Bauer, S. et al. 25th anniversary article: A soft future: From robots and sensor skin to energy harvesters. Adv. Mater. 26, 149–162 (2014).
Pang, C., Lee, C. & Suh, K. Y. Recent advances in flexible sensors for wearable and implantable devices. J. Appl. Polym. Sci. 130, 1429–1441 (2013).
Nezakati, T., Seifalian, A., Tan, A. & Seifalian, A. M. Conductive polymers: opportunities and challenges in biomedical applications. Chem. Rev. 118, 6766–6843 (2018).
Bihar, E. et al. Fully printed all-polymer tattoo/textile electronics for electromyography. Flex. Print. Electron. 3, 034004 (2018).
Ferrari, L. M. et al. Ultraconformable temporary tattoo electrodes for electrophysiology. Adv. Sci. 5, 1700771 (2018).
Yeo, W. H. et al. Multifunctional epidermal electronics printed directly onto the skin. Adv. Mater. 25, 2773–2778 (2013).
Huang, X., Yeo, W. H., Liu, Y. & Rogers, J. A. Epidermal differential impedance sensor for conformal skin hydration monitoring. Biointerphases 7, 1–9 (2012).
Gutruf, P. & Rogers, J. A. Implantable, wireless device platforms for neuroscience research. Curr. Opin. Neurobiol. 50, 42–49 (2018).
Ferrari, L. M., Ismailov, U., Badier, J.-M., Greco, F. & Ismailova, E. Conducting polymer tattoo electrodes in clinical electro- and magneto-encephalography. npj Flex. Electron. 4, 1–9 (2020).
Webb, R. C. et al. Ultrathin conformal devices for precise and continuous thermal characterization of human skin. Nat. Mater. 12, 938–944 (2013).
Bariya, M., Nyein, H. Y. Y. & Javey, A. Wearable sweat sensors. Nat. Electron. 1, 160–171 (2018).
Chung, H. J. et al. Stretchable, multiplexed pH sensors with demonstrations on rabbit and human hearts undergoing ischemia. Adv. Healthc. Mater. 3, 59–68 (2014).
Miyamoto, A. et al. Inflammation-free, gas-permeable, lightweight, stretchable on-skin electronics with nanomeshes. Nat. Nanotechnol. 12, 907–913 (2017).
Gong, S. et al. Local crack-programmed gold nanowire electronic skin tattoos for in-plane multisensor integration. Adv. Mater. 31, 1–8 (2019).
Ershad, F. et al. Ultra-conformal drawn-on-skin electronics for multifunctional motion artifact-free sensing and point-of-care treatment. Nat. Commun. 11, 3823 (2020).
Pan, C. et al. Visually imperceptible liquid-metal circuits for transparent, stretchable electronics with direct laser writing. Adv. Mater. 30, 1706937 (2018).
Childres, I., Jauregui, L. A., Tian, J. & Chen, Y. P. Effect of oxygen plasma etching on graphene studied using Raman spectroscopy and electronic transport measurements. New J. Phys. 13, 025008 (2011).
Liu, N. et al. Ultratransparent and stretchable graphene electrodes. Sci. Adv. 3, e1700159 (2017).

Fabrication, characterization and applications of graphene electronic tattoos

Supplementary information

推荐阅读