Coculture of primary human colon monolayer with human gut bacteria

Jianbo Zhang, Victor Hernandez-Gordillo, Martin Trapecar, Charles Wright, Mao Taketani, Kirsten Schneider, Wen Li Kelly Chen, Eric Stas, David T. Breault, Rebecca L. Carrier, Christopher A. Voigt, Linda G. Griffith

Published: 2021-06-27 DOI: 10.1038/s41596-021-00562-w

Coculture

Human colon monolayer

Gut bacteria

Microenvironment

Intestinal barrier

AI 解读

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The presence of microbes in the colon impacts host physiology. Therefore, microbes are being evaluated as potential treatments for colorectal diseases. Humanized model systems that enable robust culture of primary human intestinal cellswith bacteria faci
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ACKNOWLEDGMENTS

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Coculture of primary human colon monolayer with human gut bacteria

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