Specificity index (pSI) calculation

Peter Kilfeather

Published: 2024-02-07 DOI: 10.17504/protocols.io.8epv5x8mjg1b/v1
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Abstract

Specificity index (pSI) calculation from Kilfeather, Khoo et al., 2024

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To calculate the specificity index of genes detected within TRAP/RiboTag datasets of dopaminergic neurons and other cell types within midbrain, pSI (v1.1) was used with default settings22,24,38–40,73. Genes were considered significantly specifically expressed with an FDR-adjusted P value < 0.01.

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