Dual detection of chromatin accessibility and DNA methylation using ATAC-Me

Emily Hodges, Lindsey N. Guerin, Kelly R. Barnett

Published: 2021-10-17 DOI: 10.1038/s41596-021-00608-z

chromatin accessibility

DNA methylation

ATAC-Me

epigenetic dynamics

time course studies

AI 解读

Preparation of single-cell suspensions of mouse glomeruli for high-throughput analysis

cfSNV: a software tool for the sensitive detection of somatic mutations from cell-free DNA

Anaerobic cryoEM protocols for air-sensitive nitrogenase proteins

Engineering megabase-sized genomic deletions with MACHETE (Molecular Alteration of Chromosomes with Engineered Tandem Elements)

Genome-wide pooled CRISPR screening in neurospheres

Neural cell isolation from adult macaques for high-throughput analyses and neurosphere cultures

Design and fabrication of wearable electronic textiles using twisted fiber-based threads

Nacre-inspired underwater superoleophobic films with high transparency and mechanical robustness

Quantification of organelle contact sites by split-GFP-based contact site sensors (SPLICS) in living cells

Scanorama: integrating large and diverse single-cell transcriptomic datasets

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The epigenome is multidimensional, with individual molecular components operating on different levels to control transcriptional output. Techniques that combine measurements of these features can reveal their precise correspondence in genomic space, or te
Introduction
Materials
Procedure
Troubleshooting
Timing
Anticipated results
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ACKNOWLEDGMENTS

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Dual detection of chromatin accessibility and DNA methylation using ATAC-Me

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