Genome-wide measurement of DNA replication fork directionality and quantification of DNA replication initiation and termination with Okazaki fragment sequencing

Nataliya Petryk, Xia Wu, Yaqun Liu, Yves d’Aubenton-Carafa, Claude Thermes, Olivier Hyrien, Chun-Long Chen

Published: 2023-01-17 DOI: 10.1038/s41596-022-00793-5

Okazaki fragment sequencing

DNA replication

Replication fork directionality

Genome stability

Hidden Markov model

AI 解读

Supplementary information

Supplementary Information

Supplementary Protocol 1.

Reporting Summary

Purification of infection-associated macropinosomes by magnetic isolation for proteomic characterization

Hi-CO: 3D genome structure analysis with nucleosome resolution

Practical and concise synthesis of nucleoside analogs

Comprehensive analysis of glycosphingolipid glycans by lectin microarrays and MALDI-TOF mass spectrometry

Human primordial germ cell-like cells specified from resetting precursors develop in human hindgut organoids

KAS-seq: genome-wide sequencing of single-stranded DNA by N3-kethoxal–assisted labeling

Detecting chromosomal interactions in Capture Hi-C data with CHiCAGO and companion tools

Capture of the newly transcribed RNA interactome using click chemistry

Design, assembly, and characterization of membrane-spanning DNA nanopores

Transcriptome-wide identification of RNA-binding protein binding sites using seCLIP-seq

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References

Supplementary information

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Genome-wide measurement of DNA replication fork directionality and quantification of DNA replication initiation and termination with Okazaki fragment sequencing

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