Ultra-high field, multi-echo MRI acquisition for resting-state functional connectivity

Elizabeth Rizor, Dr. Scott Grafton

Published: 2024-06-28 DOI: 10.17504/protocols.io.dm6gpbbj1lzp/v1

Abstract

This is an MRI acquisition sequence used to examine resting-state functional connectivity of open and closed loop motor circuits in healthy controls and those with Parkinson’s Disease. Scans include a Localizer, anatomical T1 MPRAGE, CMRR spin-echo AP and PA echo-planar imaging (EPI) images for field map generation, and a modified CMRR multi-echo EPI sequence for resting-state imaging. All participants complete a 30-minute MRI protocol at the University of Southern California’s Center for Image Acquisition, where they are scanned with a Siemens 7T Terra scanner and a research-only ​​8-channel transmit 32-channel receive Nova 8Tx/32Rx head coil (Nova Medical Inc.)

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