Small-animal blood exchange is an emerging approach for systemic aging research

Melod Mehdipour, Payam Amiri, Chao Liu, Jonalyn DeCastro, Cameron Kato, Colin M. Skinner, Michael J. Conboy, Kiana Aran, Irina M. Conboy

Published: 2022-08-18 DOI: 10.1038/s41596-022-00731-5

Extended

Extended Data Fig. 1 Overview and detailed parts and schematics of single-pump small-animal blood exchange device.

a , Overview of single-pump small-animal blood exchange device and detailed description of the parts involved in constructing the external hardware of the pump including appropriate tubing. b , CAD image for 3D-printed hardware housing of the pump with dimensions. c , Exploded view of the single pump illustrating the intersection of the incorporated components. d , Single-pump electrical wiring diagram.

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Fabrication of angstrom-scale two-dimensional channels for mass transport

Efficient and strand-specific profiling of replicating chromatin with enrichment and sequencing of protein-associated nascent DNA in mammalian cells

The eINTACT method for studying nuclear changes in host plant cells targeted by bacterial effectors in native infection contexts

Rapid reaction optimization by robust and economical quantitative benchtop19F NMR spectroscopy

Profiling native pulmonary basement membrane stiffness using atomic force microscopy

Photoimmunotechnology as a powerful biological tool for molecular-based elimination of target cells and microbes, including bacteria, fungi and viruses

Measuring key human carbohydrate digestive enzyme activities using high-performance anion-exchange chromatography with pulsed amperometric detection

Neural cell isolation from adult macaques for high-throughput analyses and neurosphere cultures

Preparation, validation and use of a vasoactive tryptophan-derived hydroperoxide and relevant control compounds

Neuronal subtype-specific growth cone and soma purification from mammalian CNS via fractionation and fluorescent sorting for subcellular analyses and spatial mapping of local transcriptomes and proteomes

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Small-animal blood exchange is an emerging approach for systemic aging research

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