Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing

Peter Ellis, Luiza Moore, Mathijs A. Sanders, Timothy M. Butler, Simon F. Brunner, Henry Lee-Six, Robert Osborne, Ben Farr, Tim H. H. Coorens, Andrew R. J. Lawson, Alex Cagan, Mike R. Stratton, Inigo Martincorena, Peter J. Campbell

Published: 2020-12-13 DOI: 10.1038/s41596-020-00437-6

laser-capture microdissection

low-input DNA sequencing

somatic mutations

genome sequencing

tissue processing

AI 解读

Supplementary information

Supplementary Information

Supplementary Data.

Author Correction: Full-length sequencing of circular DNA viruses and extrachromosomal circular DNA using CIDER-Seq

Generation of heart-forming organoids from human pluripotent stem cells

Design and fabrication of wearable electronic textiles using twisted fiber-based threads

Activation of mechanoluminescent nanotransducers by focused ultrasound enables light delivery to deep-seated tissue in vivo

Chromatin accessibility profiling by ATAC-seq

Deoxyfluorination of phenols for chemoselective18F-labeling of peptides

Author Correction: cfSNV: a software tool for the sensitive detection of somatic mutations from cell-free DNA

Human primordial germ cell-like cells specified from resetting precursors develop in human hindgut organoids

An inexpensive semi-automated sample processing pipeline for cell-free RNA extraction

Application of CHyMErA Cas9-Cas12a combinatorial genome-editing platform for genetic interaction mapping and gene fragment deletion screening

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Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing

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