On-resin multicomponent protocols for biopolymer assembly and derivatization

Daniel G. Rivera, Manuel G. Ricardo, Aldrin V. Vasco, Ludger A. Wessjohann, Erik V. Van der Eycken

Published: 2021-01-19 DOI: 10.1038/s41596-020-00445-6

Solid-phase synthesis

Multicomponent reactions

Biopolymer assembly

Derivatization

Peptide modification

AI 解读

Fabrication of angstrom-scale two-dimensional channels for mass transport

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Neural cell isolation from adult macaques for high-throughput analyses and neurosphere cultures

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Solid-phase synthesis represents the methodological showcase for technological advances such as split-and-pool combinatorial chemistry and the automated synthesis of peptides, nucleic acids and polysaccharides. These strategies involve iterative coupling
Introduction
- Challenges associated with on-resin MCRs with biopolymers
Multicomponent approaches used in different applications
Concluding remarks
- Reporting Summary
- References
References
ACKNOWLEDGMENTS

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On-resin multicomponent protocols for biopolymer assembly and derivatization

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