Imaging and optogenetic modulation of vascular mural cells in the live brain

Lei Tong, Robert A. Hill, Eyiyemisi C. Damisah, Katie N. Murray, Peng Yuan, Angelique Bordey, Jaime Grutzendler

Published: 2020-12-08 DOI: 10.1038/s41596-020-00425-w

vascular mural cells

optogenetic modulation

intravital imaging

blood–brain barrier

neurodegenerative diseases

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Supplementary information

Supplementary Information

Supplementary Figs. 1 and 2.

Reporting Summary

Genetic manipulation and immortalized culture of ex vivo primary human germinal center B cells

The cell-line-derived subcutaneous tumor model in preclinical cancer research

Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses

NovoSpaRc: flexible spatial reconstruction of single-cell gene expression with optimal transport

Genome-wide pooled CRISPR screening in neurospheres

High-throughput cultivation and identification of bacteria from the plant root microbiota

Viral crosslinking and solid-phase purification enables discovery of ribonucleoprotein complexes on incoming RNA virus genomes

Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility

Addendum: Micro-CT acquisition and image processing to track and characterize pulmonary nodules in mice

Multiplexed single-cell proteomics using SCoPE2

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Imaging and optogenetic modulation of vascular mural cells in the live brain

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