High-resolution in situ structure determination by cryo-electron tomography and subtomogram averaging using emClarity

Tao Ni, Thomas Frosio, Luiza Mendonça, Yuewen Sheng, Daniel Clare, Benjamin A. Himes, Peijun Zhang

Published: 2022-01-11 DOI: 10.1038/s41596-021-00648-5

3D density maps

cryo-electron tomography

subtomogram averaging

emClarity

macromolecular complexes

AI 解读

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Cryo-electron tomography and subtomogram averaging (STA) has developed rapidly in recent years. It provides structures of macromolecular complexes insitu and in cellular context at or below subnanometer resolution and has led to unprecedented insights in
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ACKNOWLEDGMENTS

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High-resolution in situ structure determination by cryo-electron tomography and subtomogram averaging using emClarity

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