Engineering megabase-sized genomic deletions with MACHETE (Molecular Alteration of Chromosomes with Engineered Tandem Elements)

Francisco M. Barriga, Scott W. Lowe

Published: 2024-02-07 DOI: 10.1038/s41596-024-00953-9

CRISPR-Cas9

MACHETE

genomic deletions

selection cassette

site-specific nucleases

AI 解读

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References

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Engineering megabase-sized genomic deletions with MACHETE (Molecular Alteration of Chromosomes with Engineered Tandem Elements)

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