Annotating genetic variants to target genes using H-MAGMA Nancy Y. A. Sey, Brandon M. Pratt, Hyejung Won Published: 2022-10-25 DOI: 10.1038/s41596-022-00745-z Hi-C Genetic variants H-MAGMA Genomic annotation Complex traits AI 解读 浏览 1241 PDFMetadata 暂无数据 推荐阅读 Nature Protocols Protocols IO Current Protocols Preparation of single-cell suspensions of mouse glomeruli for high-throughput analysis cfSNV: a software tool for the sensitive detection of somatic mutations from cell-free DNA Anaerobic cryoEM protocols for air-sensitive nitrogenase proteins Engineering megabase-sized genomic deletions with MACHETE (Molecular Alteration of Chromosomes with Engineered Tandem Elements) Genome-wide pooled CRISPR screening in neurospheres Neural cell isolation from adult macaques for high-throughput analyses and neurosphere cultures Design and fabrication of wearable electronic textiles using twisted fiber-based threads Nacre-inspired underwater superoleophobic films with high transparency and mechanical robustness Quantification of organelle contact sites by split-GFP-based contact site sensors (SPLICS) in living cells Scanorama: integrating large and diverse single-cell transcriptomic datasets 查看全部 Image Registration of MALDI IMS to Microscopy HuBMAP BIOMIC Vanderbilt Multimodal Imaging IMS Image Registration Creating Differential Transcript Expression Results with DESeq2 DESeq2 nanopore transcript DE expression Fiber Photometry Acquisition ASAPCRN Optogenetic mouse brain Nielsen and Ford (2023) M4-mediated cholinergic transmission is reduced in parkinsonian mice and its restoration alleviates motor deficits and levodopa-induced dyskinesia ASAPCRN Determining Genome Targeting Efficiency using T7 Endonuclease I (M0302) T7 Endonuclease I targeting efficiency PCR and gel electrophoresis Cryo-EM sample preparation for RCKW:DARPin complex cryo-EM LRRK2 structural biology ASAPCRN Quantification of SARS-CoV-2 variant mutations (HV69-70, E484K/N501Y, del156-157/R158G, del143-145, and LPPA24S) in settled solids using digital RT-PCR SARS-CoV-2 wastewater alpha beta gamma variant mutation COVID-10 Mime-seq 2.0: a method to sequence microRNAs from specific mouse cell types miRNAs miRNA sequencing miRNA methylation miRNA profiling rare cell types mammalian system B cells Inhibitor-free DNA extraction from soil and sediment samples 查看全部 Exploring Non-Coding RNAs in RNAcentral Galaxy ncRNA non-coding RNA RNAcentral RNA-seq Purification of SRSF1 from E. coli for Biophysical and Biochemical Assays intrinsically disordered proteins NMR phase separation phosphorylation RNA splicing SR protein SRSF1 Rapid Tagging of Human Proteins with Fluorescent Reporters by Genome Engineering using Double-Stranded DNA Donors Cas9 CRISPR double-stranded DNA donors fluorescent protein genome engineering homology-directed repair tissue culture cells Engineering Ligand and Receptor Pairs with LIPSTIC to Track Cell-Cell Interactions cell-cell interactions enzymatic labeling immune interactions LIPSTIC Streptozotocin-Induced Diabetic Models in Mice and Rats high-fat hyperglycemia insulin deficiency insulin resistance insulitis mouse or rat nicotinamide streptozotocin type 1 diabetes mellitus type 2 diabetes mellitus Solid-Supported Membrane (SSM)-Based Electrophysiology Assays Using Surface Electrogenic Event Reader Technology (SURFE²R) in Early Drug Discovery drug discovery high-throughput screening solid-supported membrane (SSM)-based electrophysiology SURFE²R assay Cassava Metabolomics and Starch Quality chemotypes Manihot esculenta metabolite classification metabolite profiling metabolomics Assessing Protein Synthesis and Degradation Rates in Arabidopsis thaliana Using Amino Acid Analysis 13CO2 labeling protein degradation protein synthesis The COPILOT Raw Illumina Genotyping QC Protocol docker genotyping GWAS Illumina QC pipeline The MegaPool Approach to Characterize Adaptive CD4+ and CD8+ T Cell Responses AIM epitopes infectious diseases lyophilization SARS-CoV-2 T cell 查看全部
