An end-to-end workflow for nondestructive 3D pathology

Adam K. Glaser, Jonathan T. C. Liu, Joshua C. Vaughan, Kevin W. Bishop, Lindsey A. Erion Barner, Qinghua Han, Elena Baraznenok, Lydia Lan, Chetan Poudel, Gan Gao, Robert B. Serafin, Sarah S. L. Chow, Andrew Janowczyk, David Brenes, Hongyi Huang, Dominie Miyasato, Lawrence D. True, Soyoung Kang

Published: 2024-01-23 DOI: 10.1038/s41596-023-00934-4

data processing

3D pathology

light-sheet microscopy

tissue preparation

fluorescent staining

AI 解读

The GFP thermal shift assay for screening ligand and lipid interactions to solute carrier transporters

Co-fractionation–mass spectrometry to characterize native mitochondrial protein assemblies in mammalian neurons and brain

Simultaneously measuring the methylation of parent and daughter strands of replicated DNA at the single-molecule level by Hammer-seq

The Nodewalk assay to quantitate chromatin fiber interactomes in very small cell populations

Nondestructive production of exosomes loaded with ultrathin palladium nanosheets for targeted bio-orthogonal catalysis

An optimized culture system for efficient derivation of porcine expanded potential stem cells from preimplantation embryos and by reprogramming somatic cells

Engineering SARS-CoV-2 using a reverse genetic system

cfSNV: a software tool for the sensitive detection of somatic mutations from cell-free DNA

Growing and making nano- and microcrystals

Composable microfluidic spinning platforms for facile production of biomimetic perfusable hydrogel microtubes

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References

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An end-to-end workflow for nondestructive 3D pathology

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