Affinity-based profiling of endogenous phosphoprotein phosphatases by mass spectrometry

Brooke L. Brauer, Kwame Wiredu, Sierra Mitchell, Greg B. Moorhead, Scott A. Gerber, Arminja N. Kettenbach

Published: 2021-09-12 DOI: 10.1038/s41596-021-00604-3

mass spectrometry

phosphoprotein phosphatases

chemical proteomics

PIB-MS

PPPome

AI 解读

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Phosphoprotein phosphatases (PPPs) execute >90% of serine/threonine dephosphorylation in cells and tissues. While the role of PPPs in cell biology and diseases such as cancer, cardiac hypertrophy and Alzheimer’s disease is well established
Introduction
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References
ACKNOWLEDGMENTS
ACKNOWLEDGMENTS

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Affinity-based profiling of endogenous phosphoprotein phosphatases by mass spectrometry

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