Washington University SenNet Case Collection Protocol

Study coordinator will receive surgeon schedules at the beginning of each week. All surgeons should be IRB approved for the study.

Study coordinator will call potential study participants over phone using IRB approved phone script to see if participants are interested. Other option is to approach potential participants in Clinic when they are meeting with surgeon before the surgery date. Discuss with surgeon team which is best option as to not disrupt clinic flow.

Once patient is identified and interested, go over IRB approved consent form with patient. Answer all questions and allow for time if they need to think the process over. Must give patient a signed copy of consent form for their own personal records. Enter subjects into Oncore within 24 hours of consent process.

Study coordinator will evaluate patient for eligibility using criteria detailed in following sections.

Able to understand and willing to sign an IRB-approved written informed consent document* Undergoing routine surgery under general anesthesia for non-cancer diagnosis, including:

• Laparoscopic upper gastrointestinal surgery (for benign diagnosis, e.g. cholecystectomy, hernia repair) or Open abdominal surgery for similar indications. (need access to liver and omental fat)
• 18 years of age or older
• All races and ethnicities eligible
• All BMIs eligible
• Equal number of female and male donors will be accepted
• Past history of cancer and chemo are eligible

Undergoing a Cancer surgery* Currently receiving Chemo treatment

• Positive for HIV, Hepatitis B or C virus
• Under 18 years of age
• Unable to fully understand/sign consent form. (e.g. language barrier, compromised mental status)

Signed consent document saved and stored in secure location. Copy of signed consent also given to patient* Signed W9 tax form saved and uploaded for payment of participant.

• Check request form signed by PI saved and uploaded for payment of participant.