Rapid biosynthesis of glycoprotein therapeutics and vaccines from freeze-dried bacterial cell lysates

Jessica C. Stark, Thapakorn Jaroentomeechai, Katherine F. Warfel, Jasmine M. Hershewe, Matthew P. DeLisa, Michael C. Jewett

Published: 2023-06-15 DOI: 10.1038/s41596-022-00799-z

cell-free biosynthesis

glycoproteins

freeze-dried lysates

biomanufacturing

therapeutics

AI 解读

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The advent of distributed biomanufacturing platforms promises to increase agility in biologic production and expand access by reducing reliance on refrigerated supply chains. However, such platforms are not capable of robustly producing glycoproteins, whi
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ACKNOWLEDGMENTS

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Rapid biosynthesis of glycoprotein therapeutics and vaccines from freeze-dried bacterial cell lysates

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