Norovirus detection in water samples at the level of single virus copies per microliter using a smartphone-based fluorescence microscope

Soo Chung, Lane E. Breshears, Alana Gonzales, Christian M. Jennings, Christina M. Morrison, Walter Q. Betancourt, Kelly A. Reynolds, Jeong-Yeol Yoon

Published: 2021-01-28 DOI: 10.1038/s41596-020-00460-7

Norovirus detection

Smartphone-based fluorescence microscope

Paper microfluidic chip

Mobile detection

Pathogen detection

AI 解读

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Norovirus is a widespread public health threat and has a very low infectious dose. This protocol presents the extremely sensitive mobile detection of norovirus from water samples using a custom-built smartphone-based fluorescence microscope and a paper mi
Introduction
Materials
Procedure
Troubleshooting
- Troubleshooting the variations in ambient lighting
- Troubleshooting self-aggregation of particles
Timing
Anticipated results
References
ACKNOWLEDGMENTS
ACKNOWLEDGMENTS

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Norovirus detection in water samples at the level of single virus copies per microliter using a smartphone-based fluorescence microscope

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