Inducible mouse models of colon cancer for the analysis of sporadic and inflammation-driven tumor progression and lymph node metastasis

Clemens Neufert, Christina Heichler, Thomas Brabletz, Kristina Scheibe, Verawan Boonsanay, Florian R. Greten, Markus F. Neurath

Published: 2020-12-13 DOI: 10.1038/s41596-020-00412-1

Colon Cancer

Animal Models

Inflammation

Lymph Node Metastasis

Preclinical Testing

AI 解读

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Despite advances in the detection and therapy of colorectal cancer (CRC) in recent years, CRC has remained a major challenge in clinical practice. Although alternative methods for modeling CRC have been developed, animal models of CRC remain helpful when
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References
ACKNOWLEDGMENTS

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Inducible mouse models of colon cancer for the analysis of sporadic and inflammation-driven tumor progression and lymph node metastasis

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