Identification of cancer-related mutations in human pluripotent stem cells using RNA-seq analysis

Elyad Lezmi, Nissim Benvenisty

Published: 2021-08-05 DOI: 10.1038/s41596-021-00591-5

human pluripotent stem cells

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RNA-seq analysis

cancer-related mutations

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Identification of cancer-related mutations in human pluripotent stem cells using RNA-seq analysis

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Human pluripotent stem cells (hPSCs) are known to acquire genetic aberrations during invitro propagation. In addition to recurrent chromosomal aberrations, it has recently been shown that these cells also gain point mutations in cancer-related genes, pre
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ACKNOWLEDGMENTS

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Identification of cancer-related mutations in human pluripotent stem cells using RNA-seq analysis

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