Tutorial: best practices and considerations for mass-spectrometry-based protein biomarker discovery and validation

Ernesto S. Nakayasu, Marina Gritsenko, Paul D. Piehowski, Yuqian Gao, Daniel J. Orton, Athena A. Schepmoes, Thomas L. Fillmore, Brigitte I. Frohnert, Marian Rewers, Jeffrey P. Krischer, Charles Ansong, Astrid M. Suchy-Dicey, Carmella Evans-Molina, Wei-Jun Qian, Bobbie-Jo M. Webb-Robertson, Thomas O. Metz

Published: 2021-07-08 DOI: 10.1038/s41596-021-00566-6

mass spectrometry

protein biomarkers

study design

data processing

statistical analysis

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Author Correction: Full-length sequencing of circular DNA viruses and extrachromosomal circular DNA using CIDER-Seq

Generation of heart-forming organoids from human pluripotent stem cells

Design and fabrication of wearable electronic textiles using twisted fiber-based threads

Activation of mechanoluminescent nanotransducers by focused ultrasound enables light delivery to deep-seated tissue in vivo

Chromatin accessibility profiling by ATAC-seq

Deoxyfluorination of phenols for chemoselective18F-labeling of peptides

Author Correction: cfSNV: a software tool for the sensitive detection of somatic mutations from cell-free DNA

Human primordial germ cell-like cells specified from resetting precursors develop in human hindgut organoids

An inexpensive semi-automated sample processing pipeline for cell-free RNA extraction

Application of CHyMErA Cas9-Cas12a combinatorial genome-editing platform for genetic interaction mapping and gene fragment deletion screening

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Tutorial: best practices and considerations for mass-spectrometry-based protein biomarker discovery and validation

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