Kit-based synthesis of 2-deoxy-2-[18F]-fluoro-d-sorbitol for bacterial imaging

Filipa Mota, Patricia De Jesus, Sanjay K. Jain

Published: 2021-10-21 DOI: 10.1038/s41596-021-00613-2

PET imaging

Enterobacterales

18F-FDS

infection detection

solid-phase synthesis

AI 解读

暂无数据

Author Correction: Full-length sequencing of circular DNA viruses and extrachromosomal circular DNA using CIDER-Seq

Generation of heart-forming organoids from human pluripotent stem cells

Design and fabrication of wearable electronic textiles using twisted fiber-based threads

Activation of mechanoluminescent nanotransducers by focused ultrasound enables light delivery to deep-seated tissue in vivo

Chromatin accessibility profiling by ATAC-seq

Deoxyfluorination of phenols for chemoselective18F-labeling of peptides

Author Correction: cfSNV: a software tool for the sensitive detection of somatic mutations from cell-free DNA

Human primordial germ cell-like cells specified from resetting precursors develop in human hindgut organoids

An inexpensive semi-automated sample processing pipeline for cell-free RNA extraction

Application of CHyMErA Cas9-Cas12a combinatorial genome-editing platform for genetic interaction mapping and gene fragment deletion screening

查看全部

Sections

Figures

References

James, M. L. & Gambhir, S. S. A molecular imaging primer: modalities, imaging agents, and applications. Physiol. Rev. 92, 897–965 (2012).
Jain, S. K. The promise of molecular imaging in the study and treatment of infectious diseases. Mol. Imaging Biol. 19, 341–347 (2017).
Cherry, S. R. et al. Total-body imaging: transforming the role of positron emission tomography. Sci. Transl. Med. 9, eaaf6169 (2017).
International Atomic Energy Agency. IMAGINE—general data overview. https://humanhealth.iaea.org/HHW/DBStatistics/IMAGINEMaps1.html
Wangler, C. et al. One-step 18F-labeling of carbohydrate-conjugated octreotate-derivatives containing a silicon-fluoride-acceptor (SiFA): in vitro and in vivo evaluation as tumor imaging agents for positron emission tomography (PET). Bioconjug. Chem. 21, 2289–2296 (2010).
Basuli, F., Zhang, X., Jagoda, E. M., Choyke, P. L. & Swenson, R. E. Facile room temperature synthesis of fluorine-18 labeled fluoronicotinic acid-2,3,5,6-tetrafluorophenyl ester without azeotropic drying of fluorine-18. Nucl. Med. Biol. 43, 770–772 (2016).
van der Born, D. et al. Fluorine-18 labelled building blocks for PET tracer synthesis. Chem. Soc. Rev. 46, 4709–4773 (2017).
Allott, L., Barnes, C., Brickute, D., Leung, S. F. J. & Aboagye, E. O. Solid-supported cyanoborohydride cartridges for automation of reductive amination radiochemistry. React. Chem. Eng. 4, 1748–1751 (2019).
Liu, Z. et al. One-step 18F labeling of biomolecules using organotrifluoroborates. Nat. Protoc. 10, 1423–1432 (2015).
Wängler, C. et al. One-step 18F-labeling of peptides for positron emission tomography imaging using the SiFA methodology. Nat. Protoc. 7, 1946–1955 (2012).
Donnenberg, M. S. Enterobacteriaceae. in Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases (eds Mandell, G. L. et al.) 2815–2833 (Elsevier, 2010).
Centers for Disease Control and Prevention. Antibiotic Resistance Threats in the United States, 2019. https://www.cdc.gov/drugresistance/pdf/threats-report/2019-ar-threats-report-508.pdf
O’Neill, J. Tackling drug-resistant infections globally: final report and recommendations (Wellcome Trust and UK Government, 2016).
Tucker, E. W. et al. Noninvasive 11C-rifampin positron emission tomography reveals drug biodistribution in tuberculous meningitis. Sci. Transl. Med. 10, eaau0965 (2018).
Mota, F. et al. Radiotracer development for bacterial imaging. J. Med. Chem. 63, 1964–1977 (2020).
Ordonez, A. A. et al. Imaging Enterobacterales infections in patients using pathogen-specific positron emission tomography. Sci. Transl. Med. 13, eabe9805 (2021).
Gowrishankar, G. et al. Specific imaging of bacterial infection using 6″-(18)F-fluoromaltotriose: a second-generation PET tracer targeting the maltodextrin transporter in bacteria. J. Nucl. Med. 58, 1679–1684 (2017).
Weinstein, E. A. et al. Imaging Enterobacteriaceae infection in vivo with 18F-fluorodeoxysorbitol positron emission tomography. Sci. Transl. Med. 6, 259ra146 (2014).
Mutch, C. A. et al. [11C]Para-aminobenzoic acid: a positron emission tomography tracer targeting bacteria-specific metabolism. ACS Infect. Dis. 4, 1067–1072 (2018).
Ordonez, A. A. et al. A systematic approach for developing bacteria-specific imaging tracers. J. Nucl. Med. 58, 144–150 (2017).
Sellmyer, M. A. et al. Bacterial infection imaging with [(18)F]fluoropropyl-trimethoprim. Proc. Natl Acad. Sci. USA 114, 8372–8377 (2017).
Zhang, Z. et al. Positron emission tomography imaging with 2-[18F]F-p-aminobenzoic acid detects Staphylococcus aureus infections and monitors drug response. ACS Infect. Dis. 4, 1635–1644 (2018).
Petrik, M. et al. Imaging of Pseudomonas aeruginosa infection with Ga-68 labelled pyoverdine for positron emission tomography. Sci. Rep. 8, 15698 (2018).
Parker, M. F. L. et al. Sensing living bacteria in vivo using d-alanine-derived (11)C radiotracers. ACS Cent. Sci. 6, 155–165 (2020).
Vilche, M. et al. (6)(8)Ga-NOTA-UBI-29-41 as a PET tracer for detection of bacterial infection. J. Nucl. Med. 57, 622–627 (2016).
Polvoy, I., Flavell, R. R., Rosenberg, O. S., Ohliger, M. A. & Wilson, D. M. Nuclear imaging of bacterial infection: the state of the art and future directions. J. Nucl. Med. 61, 1708–1716 (2020).
Li, J., Zheng, H., Fodah, R., Warawa, J. M. & Ng, C. K. Validation of 2-(18)F-fluorodeoxysorbitol as a potential radiopharmaceutical for imaging bacterial infection in the lung. J. Nucl. Med. 59, 134–139 (2018).
Yao, S. et al. Infection imaging with (18)F-FDS and first-in-human evaluation. Nucl. Med. Biol. 43, 206–214 (2016).
Ordonez, A. A. et al. Molecular imaging of bacterial infections: overcoming the barriers to clinical translation. Sci. Transl. Med. 11, eaax8251 (2019).
Blaufox, M. D. et al. The SNMMI and EANM practice guideline for renal scintigraphy in adults. Eur. J. Nucl. Med. Mol. Imaging 45, 2218–2228 (2018).
Werner, R. A. et al. The next era of renal radionuclide imaging: novel PET radiotracers. Eur. J. Nucl. Med. Mol. Imaging 46, 1773–1786 (2019).
Toyama, Y. et al. Current and future perspectives on functional molecular imaging in nephro-urology: theranostics on the horizon. Theranostics 11, 6105–6119 (2021).
Zhu, W. et al. Biodistribution and radiation dosimetry of the Enterobacteriaceae-specific imaging probe [(18)F]fluorodeoxysorbitol determined by PET/CT in healthy human volunteers. Mol. Imaging Biol. 18, 782–787 (2016).
Werner, R. A. et al. Functional renal imaging with 2-deoxy-2-(18)F-fluorosorbitol PET in rat models of renal disorders. J. Nucl. Med. 59, 828–832 (2018).
Werner, R. A. et al. Novel functional renal PET imaging with 18F-FDS in human subjects. Clin. Nucl. Med. 44, 410–411 (2019).
Li, Z. B. et al. The synthesis of 18F-FDS and its potential application in molecular imaging. Mol. Imaging Biol. 10, 92–98 (2008).
Hasegawa, K., Koshino, K. & Higuchi, T. Facile synthesis of 2-deoxy-2-[(18) F]fluorosorbitol using sodium borohydride on aluminum oxide. J. Labelled Comp. Radiopharm. 64, 40–46 (2021).
Yao, S. et al. Infection imaging with 18F-FDS and first-in-human evaluation. Nucl. Med. Biol. 43, 206–214 (2016).
Šljukić, B., Santos, D. M., Sequeira, C. A. & Banks, C. E. Analytical monitoring of sodium borohydride. Anal. Methods 5, 829–839 (2013).

Kit-based synthesis of 2-deoxy-2-[18F]-fluoro-d-sorbitol for bacterial imaging

推荐阅读