The GFP thermal shift assay for screening ligand and lipid interactions to solute carrier transporters

Yurie Chatzikyriakidou, Do-Hwan Ahn, Emmanuel Nji, David Drew

Published: 2021-10-26 DOI: 10.1038/s41596-021-00619-w

high-throughput screening

GFP thermal shift assay

SLC transporters

ligand interactions

lipid–protein interactions

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Solute carrier (SLC) transporters represent the second-largest fraction of the membrane proteome after G-protein-coupled receptors, but have been underutilized as drug targets and the function of many members of this family is still unknown. They are tech
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ACKNOWLEDGMENTS

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The GFP thermal shift assay for screening ligand and lipid interactions to solute carrier transporters

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