Derivation of snake venom gland organoids for in vitro venom production

Hans Clevers, Jens Puschhof, Yorick Post, Joep Beumer, Harald M. Kerkkamp, Matyas Bittenbinder, Freek J. Vonk, Nicholas R. Casewell, Michael K. Richardson

Published: 2021-01-26 DOI: 10.1038/s41596-020-00463-4

organoids

snake venom

in vitro venom production

antivenom

toxin-producing cells

AI 解读

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Chromatin accessibility profiling by ATAC-seq

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Human primordial germ cell-like cells specified from resetting precursors develop in human hindgut organoids

An inexpensive semi-automated sample processing pipeline for cell-free RNA extraction

Application of CHyMErA Cas9-Cas12a combinatorial genome-editing platform for genetic interaction mapping and gene fragment deletion screening

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More than 400,000 people each year suffer adverse effects following bites from venomous snakes. However, snake venom is also a rich source of bioactive molecules with known or potential therapeutic applications. Manually ‘milking’ snakes i
Introduction
Materials
Procedure
Troubleshooting
Timing
Anticipated results
- Reporting Summary
References
ACKNOWLEDGMENTS

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Derivation of snake venom gland organoids for in vitro venom production

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